Firm profile

OPALEYE MANAGEMENT INC.

BOSTON, MACRD 124513Latest ADV February 19, 2026

Opaleye Management Inc. is an SEC registered investment adviser organized as a corporation with a primary office location in Boston, MA. Its latest Form ADV filing, dated February 19, 2026, reports $803M in regulatory assets under management, 4 employees, 1 office, and 2 accounts.

Assets Under Management
$803M
Employees
4
Offices
1 office
Total Clients
<5
Primary office
BOSTON, MA
ONE BOSTON PLACE, 26TH FLOOR, BOSTON, MA, United States
ADV Item 1F location record

Contact and digital presence

ADV profile links
Phone(617) 229-5085
WebsiteNot reported
LinkedInNot reported

Leadership

1 roles identified
CCOJames A. Silverman

Advisory services offered

2 types reported
Portfolio management for businesses
Portfolio management for pooled investment vehicles

Fee models offered

2 types reported
Asset based fees
Performance-based fees
Sources checked May 14, 2026

Client Coverage Demographics

Top client segmentPooled Investment Vehicles represent 50.0% of total clients.
Top client categories% of clientsClients
1
Pooled Investment Vehicles
50.0%
1
2
Corporations
50.0%
1
Categories with <5 clients
Corporations or other businesses not listed above<5 clients

Regulatory Assets Under Management Breakdown

Total regulatory assets under management$803Mas of February 19, 2026
Discretionary100.0%
$803M
100% of total RAUM100.0%
Non-discretionary0.0%
$0
0% of total RAUM0.0%
All regulatory assets under management are discretionary.

Assets under management Growth by Quarter

Quarterly points use the latest ADV filing or SEC roster snapshot available in each quarter.

Latest AUM$803M
Total Accounts2
10Y AUM Change+$618M (+334.1%)

Employee Growth by Quarter

Quarterly points use the latest ADV filing or SEC roster snapshot available in each quarter.

Total Employees4
Clients per Employee1:1
10Y Employee Change+1 (+33.3%)

* Metrics are based on the latest available data, including Form ADV filings, brochures, and relationship summaries pulled from the SEC IAPD, and may be subject to change. Learn what is included in the Rialytix data. Please refer to the firm's official disclosures for the most accurate information using their CRD number. This is not investment advice.